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Loneliness 'fuels breast cancer', say scientists

Wednesday, December 09, 2009 WASHINGTON: Being lonely could more than treble a woman's odds of developing breast cancer, research suggests. Isolation may also dramatically increase the number of tumours and their size. Although the findings were made in animal tests, the researchers believe they have important implications for human health. With loneliness already linked to a host of other illnesses from dementia to high blood pressure, they say it is important to consider a person's mental health when thinking about their physical health. The University of Chicago team looked at the effects of loneliness or 'social isolation' on female rats genetically predisposed to develop breast cancer. The breed is also one that is ' naturally gregarious', and, like humans, enjoys the company of others. The study found that animals living alone were 3.3 times more likely to develop types of breast cancer common in women than those in cages of five. The tumours were much bigger and more numerous, so that overall, the solitary rats had 84 times more cancerous tissue. The cancer also spread to most parts of the breast, the journal Proceedings of the National Academy of Sciences reports. Importantly, the spread of disease seemed to be fuelled by stress hormones, rather than the sex hormones that often drive breast cancer. Researcher Professor Martha McClintock said: 'We need to use these findings to identify potential targets for interventions to reduce cancer and its psychological and social risk factors.'

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